My ONeSource™ experience
OneSource™ was recommended to me by an advocacy organization when I initially thought I might have HPP. After reaching out to OneSource™, I was paired with a OneSource™ Case Manager. She was there to help me.”
Ray, HPP STAR
RAY, HPP STAR
Resources for people living with hpp
While living with hypophosphatasia (HPP) may be challenging, there is a community of support waiting to help. Discover the many support options available to patients and their loved ones.
HPP Support from Alexion
HPP EDUCATIONAL Events
Register for an upcoming eventTHANK YOU
We will be in touch soon.
Strensiq Specialty pharmacy support
STRENSIQ is available from a specialty pharmacy called PANTHERx Rare
Your doctor will prescribe STRENSIQ through PANTHERx Rare. This specialty pharmacy handles prescription logistics, including shipment and ongoing refills.
Read PANTHERx’s Welcome Letter to learn more.
Strensiq Treatment Support
From being prescribed STRENSIQ to starting and staying on STRENSIQ, OneSource™ and PANTHERx Rare are here to help
OneSource™ and PANTHERx Rare work together to get STRENSIQ to you or someone you care for. While OneSource™ will be your first point of contact as you make STRENSIQ part of your routine, PANTHERx Rare handles the prescription logistics and may contact you throughout treatment.
JOURNEY FROM PRESCRIPTION TO TREATMENT WITH STRENSIQ
HPP Patient Advocacy Organizations
When living with a rare disease, connecting with others is important. Get to know the groups and organizations that are dedicated to HPP and other rare diseases.
The US Hypophosphatasia Foundation and Soft Bones provide information and a community to educate, empower, and connect people, families, and caregivers living with HPP.
VISIT WEBSITE
The Avalon Foundation provides emotional and mental support to pediatric patients diagnosed with HPP and undergoing enzyme replacement therapy treatment.
VISIT WEBSITE
Global Genes builds awareness, educates the global community, and provides critical connections and resources that equip advocates to become activists for their disease.
VISIT WEBSITE
The National Organization for Rare Disorders (NORD) provides education, advocacy, research, and patient services for people with rare diseases and other organizations that serve them.
VISIT WEBSITEThe groups listed above are independent, nonprofit patient service organizations. Their listing on this website does not imply endorsement of any product or company. All logos and trademarks are the property of their respective owners.
IMPORTANT SAFETY INFORMATION INCLUDING BOXED WARNING
What is the most important information I should know about STRENSIQ?
Severe allergic (hypersensitivity) reactions have
occurred with STRENSIQ treatment and can be severe and life-threatening. Severe allergic
reactions have happened in some people within minutes
after receiving
STRENSIQ and more
than 1
year after starting
treatment with STRENSIQ.
What are the possible side effects of STRENSIQ?
STRENSIQ may cause serious side effects, including:
Severe allergic (hypersensitivity) reactions. Allergic
reactions are
common with STRENSIQ treatment and can be severe and life
threatening. Severe allergic reactions have happened in some people within
minutes after receiving STRENSIQ and more than 1 year after starting
treatment with
STRENSIQ.
Stop using STRENSIQ and go to the nearest hospital emergency room right away if you or your loved one have any of the signs and symptoms of a severe allergic reaction:
- difficulty breathing
- choking sensation
- swelling of your eyes, lips, or tongue
- itching or numbness of the
tongue, lips, cheeks, or gums - dizziness
- nausea or vomiting
Call your doctor if you experience any of the following signs and symptoms of an allergic reaction: fever, headache, sweating, feeling irritable, chills, skin redness, skin rash or hives.
Skin thickening or pits at the injection site (lipodystrophy) has happened several months after using STRENSIQ.
Calcium buildup in the eyes and kidneys. People with HPP
are at increased risk for developing calcium build-up due to disease
and may be a side
effect of STRENSIQ, although it may also occur in untreated
patients. Your healthcare provider should check your eyes and kidneys
before
and during
treatment with STRENSIQ.
Immune-related effects. You may develop antibodies
during
treatment that may decrease how well STRENSIQ works. Tell your healthcare provider right away if you get worsening symptoms of HPP including
difficulty breathing or walking, feeling tired, bone pain, stiff joints, or loss of appetite.
The most common side effects of STRENSIQ include local skin injection-site reactions (skin redness, bruising, color change, pain, itching, swelling, and bumps).
These are not all the possible side effects of STRENSIQ. For more information, ask your healthcare provider or pharmacist.
Before using STRENSIQ, tell your healthcare provider about all
your medical conditions, including if
you:
- have had an allergic reaction to STRENSIQ
- are pregnant or plan to become pregnant. It is not known if STRENSIQ will harm your unborn baby.
- are breastfeeding or plan to breastfeed. It is not known if STRENSIQ passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you use STRENSIQ.
Tell your healthcare provider about all the
medicines you
take,
including
prescription and over-the-counter medicines,
vitamins, and herbal
supplements.
There is a registry for people who use STRENSIQ. The purpose of this registry is to collect information about HPP and about what happens when you use STRENSIQ for a long time. For more information about this registry, talk with your healthcare provider or go to www.hppregistry.com.
Call your healthcare provider for medical advice about
side effects. To report SUSPECTED SIDE EFFECTS, contact Alexion
Pharmaceuticals, Inc. at
1-844-259-6783 or FDA at
1- 800-FDA-1088
or
www.fda.gov/
medwatch
Please see the full Prescribing Information,
and Patient Information for STRENSIQ
(asfotase
alfa), including Boxed
WARNING regarding severe allergic
(hypersensitivity) reaction
INDICATION
What is STRENSIQ?
STRENSIQ® (asfotase alfa) is a prescription medicine
used to
treat people
with perinatal, infantile, and juvenile onset
hypophosphatasia (HPP).
IMPORTANT SAFETY INFORMATION INCLUDING BOXED WARNING
What is the most important information I should know about STRENSIQ?
Severe allergic (hypersensitivity) reactions have
occurred with STRENSIQ treatment and can be severe and life-threatening. Severe allergic
reactions have happened in some people within minutes
after receiving
STRENSIQ and more
than 1
year after starting
treatment with STRENSIQ.
What are the possible side effects of STRENSIQ?
STRENSIQ may cause serious side effects, including:
Severe allergic (hypersensitivity) reactions. Allergic
reactions are
common with STRENSIQ treatment and can be severe and life
threatening. Severe allergic reactions have happened in some people within
minutes after receiving STRENSIQ and more than 1 year after starting
treatment with
STRENSIQ.
Stop using STRENSIQ and go to the nearest hospital emergency room right away if you or your loved one have any of the signs and symptoms of a severe allergic reaction:
- difficulty breathing
- choking sensation
- swelling of your eyes, lips, or tongue
- itching or numbness of the
tongue, lips, cheeks, or gums - dizziness
- nausea or vomiting
Call your doctor if you experience any of the following signs and symptoms of an allergic reaction: fever, headache, sweating, feeling irritable, chills, skin redness, skin rash or hives.
Skin thickening or pits at the injection site (lipodystrophy) has happened several months after using STRENSIQ.
Calcium buildup in the eyes and kidneys. People with HPP
are at increased risk for developing calcium build-up due to disease
and may be a side
effect of STRENSIQ, although it may also occur in untreated
patients. Your healthcare provider should check your eyes and kidneys
before
and during
treatment with STRENSIQ.
Immune-related effects. You may develop antibodies
during
treatment that may decrease how well STRENSIQ works. Tell your healthcare provider right away if you get worsening symptoms of HPP including
difficulty breathing or walking, feeling tired, bone pain, stiff joints, or loss of appetite.
The most common side effects of STRENSIQ include local skin injection-site reactions (skin redness, bruising, color change, pain, itching, swelling, and bumps).
These are not all the possible side effects of STRENSIQ. For more information, ask your healthcare provider or pharmacist.
Before using STRENSIQ, tell your healthcare provider about all
your medical conditions, including if
you:
- have had an allergic reaction to STRENSIQ
- are pregnant or plan to become pregnant. It is not known if STRENSIQ will harm your unborn baby.
- are breastfeeding or plan to breastfeed. It is not known if STRENSIQ passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you use STRENSIQ.
Tell your healthcare provider about all the
medicines you
take,
including
prescription and over-the-counter medicines,
vitamins, and herbal
supplements.
There is a registry for people who use STRENSIQ. The purpose of this registry is to collect information about HPP and about what happens when you use STRENSIQ for a long time. For more information about this registry, talk with your healthcare provider or go to www.hppregistry.com.
Call your healthcare provider for medical advice about
side effects. To report SUSPECTED SIDE EFFECTS, contact Alexion
Pharmaceuticals, Inc. at
1-844-259-6783 or FDA at
1- 800-FDA-1088
or
www.fda.gov/
medwatch
Please see the full Prescribing Information,
and Patient Information for STRENSIQ
(asfotase
alfa), including Boxed
WARNING regarding severe allergic
(hypersensitivity) reaction
INDICATION
What is STRENSIQ?
STRENSIQ® (asfotase alfa) is a prescription medicine
used to
treat people
with perinatal, infantile, and juvenile onset
hypophosphatasia (HPP).